The purpose with this study is to investigate the preventative effect of a supplement containing a combination of probiotic bacteria and fungi as well as zinc on the common cold. The hypothesis is that it will shorten the duration, alleviate the severity of symptoms or even decrease the number of infectons during the intervention period. This study is a randomzed placebo controlled human study were healthy adults will consume the supplement for three months.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
100
Lunds universitet
Lund, Sweden
Symptoms severity
Decrease in the severity of symptoms will be determined using a common cold questionnaire.
Time frame: Three months
Composition of gut and oral microbiome
Change in gut and oral microbiome will be measured using 16SrRNA and 18SrRNA sequencing
Time frame: Three months
IgA
Changes in levels of IgA in saliva and/or feces will be measured using ELISA
Time frame: Three months
Duration of symptoms
Decrease in duration of cold will be determined using a common cold questionnaire
Time frame: Three months
Number of colds
Decrease in number of colds will be determined using a common cold questionnaire
Time frame: Three months
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