Dose-Response Study to Evaluate the Effect of BKR-017 on Insulin Resistance and Other Metabolic Parameters in Type 2 Diabetes Patients

Inclusion Criteria: * Males and females between the ages of 18 and 70 years at the time of screening, inclusive * Diagnosed with T2D and under the care of a healthcare professional for its management, or newly diagnosed (as participant in the study) with T2D * HbA1c 6.5% -10.5%, inclusive * Has given written informed consent to participate in this study * Willing to complete 84-day test period * Willing to maintain current diet and exercise routine and current prescription medications for the duration of the study Exclusion Criteria: * Type 1 diabetes * History of bariatric or intestinal surgery * Active gastrointestinal disease including but not limited to irritable bowel syndrome, inflammatory bowel disease (e.g., Crohn's disease and ulcerative colitis), diverticulitis, gastroparesis * Active and clinically significant hepatic, pancreatic disease, or renal disease as determined by the investigator * History of heart disease that in the opinion of the investigator should exclude the subject from the study * Severely uncontrolled hypertension at screening defined as a systolic blood pressure \> 180 mmHg or a diastolic blood pressure \> 110 mmHg on the average of two seated measurements after being at rest for at least 5 minutes * Untreated or uncontrolled hyperthyroidism or hypothyroidism, or other significant thyroid disease * Active significant infection as determined by the investigator * Known allergy to butyrate or any of the components of the tablets * Subjects planning to make major changes to diet and physical activity during the trial duration * Participation in a clinical trial and/or treatment with an investigational drug during the 30 days before screening, or within 5 half-lives of receipt of an investigational drug or twice the duration of the biological effect of any investigational drug (whichever is longer) * Pregnant, nursing, or trying to become pregnant * In the investigator's judgment, the subject is not suitable for the study for any other reason or cannot commit to the requirements of the study. * Subject is taking one or more of the excluded therapies.