The Prevalence and Characteristics of Adrenal Incidentaloma

Chongqing Medical University25,356 enrolled

Overview

To investige the prevalence, characteristics and prognosis of adrenal incidentalomas in Chinese adults.

With the development of imaging detection technology and its wide application in clinic, the detection rate of adrenal incidentaloma (AI) has been greatly improved. Most AI are benign and do not have the function of autonomic hormone secretion, but about 20% of them have function and can secrete adrenal hormone autonomously. Studies based on biopsy reports show that the prevalence of AI is about 2%, and the prevalence of AI detected by CT scan is 1% - 4.5%. However, most of these studies are retrospective, and there may be selection bias and other confounding factors. There is no large sample prospective study on the prevalence of AI in the general population. The purpose of this study is to prospectively include patients with adrenal incidentaloma in community physical examination population, and evaluate their function and prognosis. The research results will provide new evidence for standardized diagnosis and treatment of adrenal incidentaloma in the future.

Study Type

OBSERVATIONAL

Enrollment

25,356

Conditions

Prevalence Adrenal Incidentaloma

Eligibility

Sex: ALLMin age: 18 YearsMax age: 78 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: ·On weekdays, the first 100 individuals, aged 18 to 78 years, taking health checkup in the Community Health Examination Center were invited to take part in the study. Exclusion Criteria: * with known adrenal diseases; * with continuous steroids or drug treatment that might influence cortisol secretion ordexamethasone metabolism and could not be stopped * refuse to participate in the study.

Locations (1)

the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

Chongqing, Chongqing Municipality, China

Outcomes

Primary Outcomes

Prevalence and Characteristics of Adrenal Incidentaloma

To investigate the prevalence and characteristics of Adrenal Incidentaloma in general population in China

Time frame: 1 years

Secondary Outcomes

Steroid hormones in the function of Adrenal Incidentaloma

prospectively evaluate potential predictive role of combined detection of multiple steroid hormones in the function of Adrenal Incidentaloma

Time frame: 1 years

Data from ClinicalTrials.gov

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