Intraoperative NIRS of Transplanted Kidney for Prediction of Acute and Sub-acute Injury

Tel-Aviv Sourasky Medical Center60 enrolled

Overview

This is a prospective, observational cohort study, designed to explore the use of NIRS in kidney transplants. This study will investigate an association between measurements of intra- operative NIRS and post - operative graft dysfunction as manifested in initiation of renal replacement therapy.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Graft Failure

Interventions

Invos Model 5100C Cerebral/Somatic OximeterDEVICE

To measure the correlation between post arterial and venous anastomoses (reperfusion) NIRS values of transplanted kidney and post-transplant graft failure as manifested in initiation of renal replacement therapy post transplant

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Kidney transplant candidates (living/ cadaver donor) at TLVMC who will consent to participate. Exclusion Criteria: * Patients unable to give consent, * patients whose surgeries were aborted before transplant, * patients who were lost to follow up during the first 7 post-transplant days, * patients who suffered from surgical graft failure (vascular problems or need for re exploration due to bleeding etc.) * No pregnant patients will participate in this study. * No minors will participate in this study.

Outcomes

Primary Outcomes

Graft Failure

Initiation of renal replacement therapy

Time frame: 7 days post operative

Graft Failure

Initiation of renal replacement therapy

Time frame: 6 months post operative

Central Contacts

Orr Goren, Dr

CONTACT

+972527360330 org@tlvmc.gov.il

Data from ClinicalTrials.gov

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