The objective of the proposed study is to investigate the effect of cinnamon on the postprandial glycemic response to a high glycemic index meal in normal and overweight/obese prediabetic subjects
A randomized crossover study design will be carried out in accordance with the guidelines of the Human Subjects Protection Committee of the University of California, Los Angeles. All subjects will give written informed consent before the study begins. There will be two groups of participants (normal and overweight/obese). Each participant will consume oatmeal prepared with 1 cup of 2% milk served with or without 6 g of ground cinnamon in random sequence. At each meal consumption blood will be collected to measure postprandial glucose and insulin at 0, 30, 60, 90, 120, 150 and 180 minutes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
32
6 g of ground cinnamon
UCLA Center for Human Nutrition
Los Angeles, California, United States
glucose
postprandial glucose reponse
Time frame: Baseline to 180 minutes
insulin
postprandial insulin response
Time frame: Baseline to 180 minutes
C-peptide
postprandial C-peptide response
Time frame: Baseline to 180 minutes
glucagon
postprandial glucagon reponse
Time frame: Baseline to 180 minutes
lipids
postprandial lipid response
Time frame: Baseline to 180 minutes
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