Transcutaneous Auricular Vagus Nerve Stimulation Treatment on Meniere Disease

Beijing Tongren Hospital25 enrolled

Overview

Objective: To evaluate the effect of Transcutaneous auricular vagus nerve stimulation for the patients Meniere disease. Methods: We accrued 25 patients at Beijing TongRen Hospital. All treatments were self-administered by the patients at home after training at the hospital. Patients completed questionnaires at baseline and after 4 weeks, 8 weeks, 12 weeks. Tinnitus Handicap Inventory (THI), Dizziness Handicap Inventory (DHI), Pure Tone Audiometry, visual scale of ear stuffiness and SF-36 were performed to evaluate the therapeutic effects. A difference of P \< 0.05 was considered statistically significant.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Meniere Disease

Interventions

taVNS

taVNS was applied using a Huatuo stimulator (SDZ-IIB) developed by Suzhou manufacture of Medical Device and Material. Stimulation parameters was 1 mA of electrical current at a frequency of 20 Hz with pulse duration ≤ 1 ms, for 30min,administered twice daily.

Eligibility

Sex: ALLMin age: 40 YearsMax age: 66 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Age \>=18 and Age \<=70. 2. Clinical diagnosis of meniere disease. Exclusion Criteria: 1. History of depression, tumors, thyroid disease, diabetes, cardiac diseases. 2. History of Otorhinolaryngology surgery. 3. Pregnant or lactating women.

Locations (1)

Beijing Tongren Hospital

Beijing, China

Outcomes

Primary Outcomes

Mean change from Baseline in the Tinnitus Handicap Inventory (THI) rating scale at 12 Weeks

Tinnitus Handicap Inventory (THI) to measure the subjective tinnitus symptoms. Tinnitus Handicap Inventory (THI) to measure the subjective tinnitus symptoms