OCTA and Retinal Angiomatous Proliferation

Federico II University118 enrolled

Overview

To investigate, using optical coherence tomography angiography, the retinal vascular features in patients affected by RAP.

Retinal vascular anomalous complex represents a distinct form of neovascularization in patients with age-related macular degeneration. The study investigated the changes in retinal vascular network using optical coherence tomography angiography, a novel and non invasive diagnostic technique that allows to better understand the pathophysiologic mechanism of this neovascularization.

Study Type

OBSERVATIONAL

Enrollment

118

Conditions

Age Related Macular Degeneration

Interventions

optical coherence tomography angiographyDIAGNOSTIC_TEST

optical coherence tomography aniography is a non-invasive, fast, diagnostic imaging technique that evaluates the retinal vascular network

Eligibility

Sex: ALLMin age: 65 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * age older than 65 years * diagnosis of retinal angiomatous proliferation and reticular pseudodrusen * absence of previous ocular surgery, congenital eye disease, high myopia (\>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases. * absence of significant lens opacities, low-quality OCT-A images. Exclusion Criteria: * age older than 80 years * absence of diagnosis of retinal angiomatous proliferation and reticular pseudodrusen * presence of previous ocular surgery, congenital eye disease, high myopia (\>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases. * presence of significant lens opacities, low-quality OCT-A images.

Locations (1)

Federico II University

Naples, Napoli, Italy

Outcomes

Primary Outcomes

The measurements of retinal vascular network in patients with age-related macular degeneration, using optical coherence tomography angiography, compared to controls

The parameters analyzed by optical coherence tomography angiography were: vessel density of superficial capillary plexus and deep capillary plexus

Time frame: 15 months

Data from ClinicalTrials.gov

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