Effect of Different Concentrations of Lidocaine in Relieving Pain in Wide Awake Hand Surgery Using Tumescence

King Edward Medical University90 enrolled

Overview

Lidocaine has been used along with adrenaline in tumescent anesthesia for a variety of procedures. This has been quite popular especially in wide awake surgery of the hand with no tourniquet. However, the appropriate lidocaine concentration is yet to be established. This randomized control trial will study the minimum effective lidocaine concentration in hand surgery using the tumescent technique.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Lidocaine

Interventions

lidocaineDRUG

different concentrations of lidocaine with same concentration of adrenaline

Eligibility

Sex: ALLMin age: 16 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients aged 16 to 60 years of either gender 2. Patients with post burn/post traumatic contractures involving fingers \& palm 3. Patients with nerve injury or flexor/extensor tendons injury distal to mid forearm. Exclusion Criteria: 1. Patients with history of ischemic heart disease, chronic liver disease (ALT/AST 40 IU/L), renal disease (creatinine 13mg/dl), bleeding disorder, peripheral arterial disease \& peripheral neuro3pathy . 2. Surgical site infection . 3. History of allergic hypersensitivity to epinephrine or lidocaine.

Locations (1)

Department of plastic Surgery,Mayo Hospital King Edward Medical University

Lahore, Pujab, Pakistan

Outcomes

Primary Outcomes

total duration of analgesia

Patients were randomized to either 0.1percent, 0.2 percent and 0.3 percent groups. Tumescent local anesthesia was infiltered. Surgery was started approximately 25 minutes after the infiltration. Start of surgery was designated 0 minute. Duration of pain free surgery was noted in minutes. Pain scores was measured after surgery. When pain scores was equal to or more than 4, analgesia was given and total time in minute from start of surgery till this time was taken as total duration of analgesia.

Time frame: Within 24 hours of randomization.

Data from ClinicalTrials.gov

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