The Effect of Embryo Culture Under a Continuous CO2 Setting Versus a Sequential CO2 Setting

Reproductive Medicine Associates of New Jersey102 enrolled

Overview

The purpose of this study is to determine if embryo culture under a single CO2 setting improves blastocyst formation rate.

Following enrollment, patients will undergo ovarian stimulation and oocyte retrieval per routine as previously consented to at the clinic. IVF stimulation protocol will be at the discretion of the patient's individual provider, per routine. Intracytoplasmic Sperm Injection (ICSI) will be performed and embryos will be cultured to the blastocyst stage per routine. There are no changes to the embryology care itself, the only difference within the study is the CO2 level within the incubator pending the patient's randomization.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

QUADRUPLE

Enrollment

102

Conditions

Infertility

Interventions

Continuous CO2 LevelOTHER

Embryos will be cultured in a single, continuous CO2 setting

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Major Inclusion Criteria for participants: 1\. Patients undergoing IVF stimulation cycle with plan for subsequent FET Major Exclusion Criteria for participants: 1. All patients who do not voluntarily give their written consent for participation 2. Male partner with \<100,000 total motile spermatozoa per ejaculate (donor sperm is acceptable) 3. Use of surgical procedures to obtain sperm

Locations (1)

Reproductive Medicine Associates of New Jersey

Basking Ridge, New Jersey, United States

Outcomes

Primary Outcomes

blastulation rate

the number of zygotes that reach the blastocyst stage

Time frame: approximately one week

Data from ClinicalTrials.gov

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