Effect of Left Atrial Appendage Velocity on Left Atrial Structure and Function After Radiofrequency Ablation Combined With Left Atrial Appendage Occlusion

The Second Hospital of Hebei Medical University100 enrolled

Overview

Radiofrequency ablation of atrial fibrillation combined with left atrial appendage closure can not only improve symptoms in patients with non-valvular atrial fibrillation, but also prevent left atrial appendage thrombosis. The safety and effectiveness of left atrial appendage occlusion have been confirmed by randomized controlled trials and actual experience. Among patients with different left atrial appendage emptying speeds, there are limited studies on the structure and function of the left atrial appendage after LAA closure. In this study, patients with persistent nonvalvular atrial fibrillation were selected for radiofrequency ablation combined with LAA closure. The sinus rhythm was restored after the operation. According to the different emptying speed of the left atrial appendage, they were divided into a high-flow rate group and a low-flow rate group. The differences in the structure and function of the left atrium between the two groups were analyzed.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Left Atrial Appendage Velocity Left Atrial Structure Left Atrial Function

Interventions

Patients with nonvalvular atrial fibrillation underwent radiofrequency ablation combined with left atrial appendage closure and recovered to sinus rhythm after the operation. To study the changes of left atrial organization and function of two groups of patients with different left atrial appendage emptying speeds.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who received atrial fibrillation radiofrequency ablation combined with left atrial appendage closure. Exclude Criteria * Patients with incomplete data. * Device embolism. * Residual shunt around the device found by transesophageal echocardiography greater than 5 mm. * Mitral valve stenosis. * Artificial valve. * Atrial septal defect. * Dilated cardiomyopathy * Moderate Severe mitral regurgitation

Outcomes

Primary Outcomes

Changes in the structure of the left atrium

Measure the left atrial transverse diameter, anteroposterior diameter, upper and lower diameter.

Time frame: 1year

Changes in the function of the left atrium

Left atrium volume. Two-chamber and four-chamber left atrium strain and strain rate, left atrium storage function, channel function and pump function.