Vitamin D Status in Children With Sickle Cell Disease Living in Lyon, France

Hospices Civils de Lyon130 enrolled

Overview

Vitamin D deficiency may be under-diagnosed in sickle cell disease French children. Therefore, the investigator need an epidemiologic study about the prevalence of vitamin D deficiency in this specific population. There are not specific guidelines neither testing nor treatment. The investigator propose to test vitamin D status in all children with sickle cell disease who are consulting their referring haematologist doctor or in the emergency ward.

Study Type

OBSERVATIONAL

Enrollment

130

Conditions

Vitamin D Deficiency Sickle Cell Disease

Interventions

25-OH Vitamin D measureBIOLOGICAL

As a complement to the off-study prescription, the investigator are taking two 1 mL tubes of extra blood to measure vitamin D, calcium, phosphorus, parathyroid hormone (PTH) and creatinine.

Eligibility

Sex: ALLMax age: 17 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Children: under 18 years old * Sickle cell any genetic type homozygous or composite heterozygous * To receive an assessment independently of the study, during a presentation to the emergency ward and/or a follow-up consultation by the hematologist * no parental opposition signed by at least one parent/legal representative and no child opposition * social security beneficiary Exclusion Criteria: * History of hematologic grafting

Locations (1)

Hôpital Femme Mère enfant - Urgences pédiatriques

Bron, France

Outcomes

Primary Outcomes

Determination of 25-OH Vitamin D level

We classify vitamin D status as follows : * Sufficiency \> \>75nmol/L (\>30 ng/mL) * Insufficiency 50-75 nmol/L (20-30 ng/mL) * Deficiency 12-50nmol/L (5-20 ng/mL) * Severe deficiency \<12 nmol/L (\<5 ng/mL)

Time frame: Day 1

Data from ClinicalTrials.gov

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