Aim of the study is comparing the effect of amino acid versus magnesium sulfate infusion on postoperative shivering in patients undergoing elective percutaneous nephrolithotomy surgery under general anesthesia.
A written informed consent was taken from the patients. Patients were assigned randomly to two groups (40 subjects each) to be anesthetized and infused with either an iv amino acid starting just before and during anesthesia (group A) or an iv magnesium sulphate starting just before and during anesthesia (group M) in the perioperative period.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
80
amino acid infusion 150 ml/kg/hr starting preoperative
magnesium sulphate bolus and infusion 60 mg/kg starting preoperative
Assiut university
Asyut, Egypt
Postoperative shivering grade
"grading of shivering," in which shivering degree was assessed as 1 of 5 levels (0, 1, 2, 3, and 4), grade 0 lack of shivering, grade 1 slight shivering (inconsiderable yet apparent peripheral vasoconstriction), grade 2 medium level shivering (muscular activity in one muscle group only) grade 3 severe shivering (muscular activity in more than one muscle group without generalized shivering) and grade 4 generalized shivering.
Time frame: 2 hours postoperative
Shivering frequency
Number of shivering episodes in postoperative period
Time frame: 2 hours postoperative
Blood loss volume
Assessing blood loss in surgical drains postoperative
Time frame: 2 hours postoperative
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