Sea Water in Allergic Conjunctivitis

Inclusion Criteria: The inclusion criteria were patients with mild or moderate allergic conjunctivitis as detailed in Table I. The minimum to be included in the study was the presence in both eyes of three symptoms and one sign (Table II). Among the symptoms, the presence of itching and two more of the following were essential: redness, tearing, foreign body sensation, rubbing, mucous secretion, and/or palpebral swelling sensation. Among the signs, conjunctival hyperemia, papillae in the palpebral conjunctiva, and/or corneal affectation in the form of dotted keratitis were evaluated. Table 1 Degree of conjunctivitis I Mild II Moderate III Severe IV Blinding Conjunctiva bulbar: congestion granuloma Conjunctiva tarsal: micropapillae 1mm giant \>1 mm cobblestone Corneal staining : micro macro shield ulcer Limbal affectation: \< 180 degrees \>180 degrees insufficiency limbo/pannus/ vascularization corneal Table 2 Signs and symptoms evaluated initially and at each visit Symptoms Signs: * Itching - Conjunctival Hyperemia * Redness - Pads * Foreign body sensation - palpebral swelling * Photophobia * Eyelid swollen sensation * Mucous secretions * Rubbing * Tears Exclusion Criteria: * blepharitis * meibomian gland dysfunction syndrome (MGS) * dry eye disease * topical eye drug such as cyclosporine, tacrolimus, interferon-alpha, mitomycin * previous eye surgery * corneal refractive surgery. * use of contact lenses * glaucoma * pterygium * ocular pemphigoid * anti-allergic vaccines * oral or subcutaneous drugs such as antihistamines, anti-leukotrienes (montelukast), corticoids, immunosuppressants or biological drugs. * rhinitis and dermatitis