We investigate the effectiveness of a combined repetitive transcranial magnetic stimulation (rTMS) - video game-based training (VBT) dexterity intervention in Parkinson's diseases. The short and long-term benefits of this training program will be evaluated. For these purposes, a blinded sham controlled randomized controlled trial will be performed.
Patients with Parkinson's disease (PD) often exhibit dexterous difficulties during the performance of activities of daily living (ADL) such as tying shoe laces, hand-writing, using remote controls, smartphone or tablet. These difficulties further add to the burden of the disease, leading to reduced quality of life (QoL). A relatively new, but rapidly growing aspect of training in PD neurorehabilitation is exergaming. To enhance training effects a combination of repetitive transcranial magnetic stimulation (rTMS) with exergaming will be tested.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
30
Non-invasive brain stimulation
Non-invasive brain stimulation
Luzerner Kantonsspital
Lucerne, Switzerland
DextQ-24
standardized patient self-rated outcome measure (PROM) for evaluating dexterity related ADL in PD
Time frame: 3 weeks
Nine Hole Peg test (9-HPT)
The 9-HPT is a standardized, well established, and reliable measure of hand dexterity in patients with PD.
Time frame: 3 weeks
Coin rotation task (CRT)
The CRT measures fine coordinated finger movements and is a suitable and valid dexterity test in patients with PD.
Time frame: 3 weeks
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