Individualized Brain Stimulation Using Transcranial Direct Current Stimulation Simulation in Stroke Patients

Samsung Medical Center24 enrolled

Overview

This study is to investigate the effect of transcranial direct current stimulation (tDCS) simulation-based individualized stimulation compared to conventional stimulation and sham stimulation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Stroke

Interventions

Transcranial Direct Current StimulationDEVICE

Transcranial direct current stimulation is a form of noninvasive neuromodulation that uses constant and low direct current delivered via electrodes on the scalp.

Eligibility

Sex: ALLMin age: 19 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Unilateral stroke patients * Chronic patients over 6 months after onset * Patients with motor evoked potential of the first dorsal interosseous muscle * Patients with the movement of fingers Exclusion Criteria: * History of psychiatric disease * Significant other neurological diseases except for stroke * Difficult to perform this experiment * Patients who are deemed difficult to participate in this research by the investigator * Patients with metal implants and medical devices * History of epilepsy * Pregnancy * Skin defect at the site of electrode attachment

Locations (1)

Samsung Medical Center

Seoul, South Korea

Outcomes

Primary Outcomes

Changes in motor evoked potential

Resting motor threshold (rMT), amplitude, and latency of motor evoked potential in the first dorsal interosseous muscle are measured. These outcomes are measured by transcranial magnetic stimulation over the motor hotspot. The rMT is defined as the minimum stimulus intensity that produced a minimal motor evoked response at rest. The amplitude means peak to peak of the muscle response. The latency is defined as the time point from the onset of the stimulus to the onset of MEP.