This study evaluate the effect of dexmedetomidine on intelligence test in pediatric patients with multiple anesthesia exposure. Children who are diagnosed with retinoblastoma and receive first exam under general anesthesia before age of 2 are included. Intelligence test will performed when patients' age are 4.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Enrollment
60
Dexmedetomidine (1 mcg/kg loading for 10 min, then 1 mcg/kg/min continuous infusion) is used with sevoflurane in every time of general anesthesia
Seoul National University Hospital
Seoul, South Korea
RECRUITINGIQ score at age of 4
Korean-Wechsler Preschool and Primary Scale of Intelligence test (score \>131, high; score 116-130, high-normal; socre 85-115, normal; score 70-84; low-normal; score \<69; low)
Time frame: year 4
Developmental Test
visual-Motor Integration test
Time frame: year 4
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