This national study will recruit expectant mothers with and without positive nasopharyngeal swabs for SARS-CoV-2, and aims to determine the seroepidemiology of SARS-CoV-2 amongst expectant mothers and their infants in the U.K.
Study Type
OBSERVATIONAL
Enrollment
881
St George's, University of London
London, United Kingdom
Antibody Concentrations in Maternal Blood in Pregnant Women in England
Antibody concentrations in maternal blood in pregnant women in England: ADCD-S values reported
Time frame: Delivery
Antibody Concentrations in Cord/Infant Blood at Delivery
Cord blood was tested to determine infant antibody levels; where a cord blood sample was not available, a blood sample was taken from the infant instead. ADCD-S assay results are presented.
Time frame: Delivery
Number of Participants With Breastmilk Samples Positive for Antibodies Specific to SARS-CoV-2
Number of participants with breastmilk samples positive for antibodies specific to SARS-CoV-2
Time frame: At birth
Number of Mother-infant Pairs Who Are Both rtPCR Positive for SARS-CoV-2 in Blood at Delivery
Time frame: Delivery
Number of Mother-infant Pairs Who Are Both rtPCR Positive for SARS-CoV-2 in Secretions at Delivery
Time frame: Delivery
Breastmilk Samples That Are rtPCR Positive
Time frame: Delivery
Placental Samples That Are rtPCR Positive
Time frame: Delivery
Number of Participants in Whose Placental Sample the Virus Can be Grown in Vitro
Time frame: Delivery
Number of Participants in Whose Breast Milk Sample the Virus Can be Grown in Vitro
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Time frame: Delivery
Number of Mother-baby Pairs in Whom the Virus Can be Grown in Vitro
Time frame: 6 weeks post delivery