Comparison of the Performance of an Optimized 3D EPI SWI Sequence and a Non-EPI QSM SWI Sequence in Detecting the Central Vein Sign in Patients With Multiple Sclerosis

Fondation Ophtalmologique Adolphe de Rothschild60 enrolled

Overview

Patients who have agreed to participate in the study will complete the MRI protocol as part of routine care, to which four additional 20-minute sequences will be added. MRI of routine care in the context of MS includes at least the following sequences: * 3D T1 TFE (2 minutes) * T2 TSE (2 minutes) * 3D FLAIR (3 minutes) * SWI EPI 0.6 iso (7 minutes) The sequences added by the search are: * SWI non EPI QSM 6 echo (10 minutes) * SWI EPI in resolution equivalent to non-EPI SWI (3 minutes) * SWI EPI to TR equivalent to SWI non EPI (6 minutes) These sequences will be acquired before or after the injection of gadolinium (if present in the examination of routine care). For examinations carried out with injection, the order of carrying out the 4 post-injection SWI sequences will be random.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Multiple Sclerosis

Interventions

cerebral MRIDEVICE

MRI of routine care in the context of MS includes at least the following sequences: * 3D T1 TFE (2 minutes) * T2 TSE (2 minutes) * 3D FLAIR (3 minutes) * SWI EPI 0.6 iso (7 minutes) The sequences added by the search are: * SWI non EPI QSM 6 echo (10 minutes) * SWI EPI in resolution equivalent to non-EPI SWI (3 minutes) * SWI EPI to TR equivalent to SWI non EPI (6 minutes)

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients over 18 * With MS defined according to the McDonald's revised clinical or radiological spatial and temporal dissemination criteria, with onset of symptoms \<5 years * To benefit as part of care from an MRI with or without injection of gadolinium * Express consent to participate in the study * Affiliate or beneficiary of a social security scheme Exclusion Criteria: * Patient benefiting from a legal protection measure * Pregnant or breastfeeding woman

Outcomes

Primary Outcomes

percentage of lesions showing the central vein sign with the SWI EPI sequence that also show the central vein sign with the candidate sequence

Time frame: 1 day

percentage of lesions which do not present the sign of the central vein with the SWI EPI sequence but which present it with the candidate sequence