Exercise Capacity, Cardiovascular Risk Factors and Disease-related Variables in Axial Spondyloarthritis

Muğla Sıtkı Koçman University76 enrolled

Overview

The investigators aimed to study the associations between exercise capacity and cardiovascular (CV) risk factors in axial spondyloarthritis (axSpA) patients and to determine possible relationships with disease-related variables. Thirty eight patients and 38 controls were recruited in our cross-sectional controlled study. Comprehensive systemic and musculoskeletal examinations were carried out in both of the groups. Cardiovascular risk profile data, ASDAS-CRP, 10-year CV event risk, physical activity levels (IPAQ) were recorded. A maximal treadmill exercise test by Bruce protocol was administered to all participants.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Exercise Capacity Axial Spondyloarthritis

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * clinical diagnosis of axial SpA * must be able to walk Exclusion Criteria: * established cardiac disease including structural heart diseases, * uncontrolled hypertension, * cardiac rhythm disorder, * unstable angina pectoris, * chronical renal and/or hepatic disease, * malignancy, * neuromuscular disease * musculoskeletal deformity * the history of an inflammatory arthritis for control group

Outcomes

Primary Outcomes

Secondary Outcomes

Mean difference in heart rate recovery of axSpA patients and controls

peak heart rate achieved by maximal exercise minus heart rate at 1st minute of recovery phase

Time frame: may- october 2014