The objective of this research is to record mood states and depression levels in healthy college students before and after 4 weeks of daily vinegar ingestion.
Recent research suggests that fruit and vegetable intake is inversely associated with mood states and depression. Although the mechanism is not known, increased gut fermentation is suspected as changes in gut tryptophan metabolism was noted in these trials. Tryptophan is the precursor to serotonin, the neurotransmitter associated with improved mood state, but other metabolites of tryptophan have been associated with mental wellbeing as well. The main ingredient of vinegar, acetic acid, is the most common metabolite produced during gut fermentation of dietary fiber (mainly from fruits and vegetables) and can also be expected to influence the gut microbiome. It has been reported that vinegar ingestion is linked to a change in tryptophan metabolism in healthy adults consuming vinegar daily for 8 weeks. This study will explore the impact of vinegar ingestion on mood states.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Enrollment
25
2 tablespoons diluted in water taken twice daily with meals
one pill taken daily
Arizona State University
Phoenix, Arizona, United States
mood state
Profile of Mood States (POMS) questionnaire score
Time frame: change from baseline at day 28
depression
Center for Epidemiologic Studies Depression Scale (CES-D)
Time frame: change from baseline at day 28
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