Antiviral T Lymphocyte Immunity During Acute COVID-19 Infection

Inclusion Criteria: * Patient with an acute SARS-CoV-2 infection, confirmed by PCR or typical CT images, requiring hospitalization in a COVID unit at the Rouen University Hospital (pneumonic form requiring oxygen therapy \< 4 L/min.) * Rouen University Hospital staff free of any symptomatology compatible with an SARS-CoV-2 infection (fever, cough, fatigue, loss of taste, loss of smell) since February 1, 2020 * Age ≥ 18 years old * Adult patient who has read and understood the information letter and signed the consent form * Affiliation to a social security scheme Exclusion Criteria: * Patient with PCR-confirmed SARS-CoV-2 infection and hospitalized in intensive care units (acute respiratory distress and/or organ failure, whose pathogenesis may differ from the more frequently described forms with secondary aggravation (5)). * Patient with PCR-confirmed but non-hospitalized SARS-CoV-2 infection (non-acute form, managed by confinement) * A person participating in a therapeutic trial that may interfere with the procedures being investigated, including lymphocyte response prior to D+56±14 days. * Known Pregnancy * Person deprived of liberty by an administrative or judicial decision or person placed under judicial protection / subtutorship or guardianship * Staff at the Rouen University Hospital with SARS-CoV-2 infection confirmed by PCR and/or typical scan images during the epidemic period. * Hospital staff who were exposed to the virus (working in a Covid unit)