Numerous epidemiological studies have investigated the association between Helicobacter pylori (H. pylori) infection and inflammatory bowel disease (IBD) with various conflicting results. The main objective of this study is to further explore the possible association between H. pylori infection and IBD and its impact on disease course. The investigators sought to conduct a prospective observational study and enroll a total of 182 IBD patients who were screened for H. pylori infection. All the participants will be clinically evaluated at the initial visit and bimonthly for 3 months. Several factors will be explored such are diet, physical activity, life style and considering specific environmental exposures that impact the development of disease or its relapse.
Study Type
OBSERVATIONAL
Enrollment
182
Follow up and observe under standard of care given
High Institute of Public Health
Alexandria, Egypt
Change in the inflammatory bowel disease condition
Change in the inflammatory bowel disease condition during follow up as measured by disease related symptoms \[weight loss where weight will be measured and reported in kilograms\]
Time frame: 3 months
Change in the inflammatory bowel disease condition
Change in the inflammatory bowel disease condition during follow up as measured by frequency of disease related symptoms \[number of attacks disease related symptoms per day (diarrhea, tenesmus, bleeding per rectum, abdominal pain, indigestion)\]
Time frame: 3 months
Change in the inflammatory bowel disease condition
Change in the inflammatory bowel disease condition during follow up as measured by changes in baseline laboratory parameters measured in serum samples \[C reactive protein (IU/ml)\]
Time frame: 3 months
Change in the inflammatory bowel disease condition
Change in the inflammatory bowel disease condition during follow up as measured by changes in baseline laboratory parameters measured in serum samples \[Hemoglobin (g/dl)\]
Time frame: 3 months
Change in the inflammatory bowel disease condition
Change in the inflammatory bowel disease condition during follow up as measured by changes in baseline laboratory parameters measured in blood samples \[Complete blood picture including white blood count per cmm, platelets count per cmm\]
Time frame: 3 months
Change in the inflammatory bowel disease condition
Change in the inflammatory bowel disease condition during follow up as measured by changes in baseline laboratory parameters measured in serum samples \[ESR (mm/hr)\]
Time frame: 3 months
Change in the inflammatory bowel disease condition
Change in the inflammatory bowel disease condition during follow up as measured by changes in baseline laboratory parameters measured in serum samples \[Fasting blood glucose (mg/dl)\]
Time frame: 3 months
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