Short-term Perioperative Thromboprophylaxis After Major Abdominal Surgery

Istanbul Medeniyet University89 enrolled

Overview

Major abdominal surgery for cancer is major risk factor for thromboembolism. Patients who undergo major abdominal surgery are prone to develop venous thromboembolism, both in the early postoperative period and after hospital discharger. There are strong recommendations in the international guidelines in favor to pharmacological thromboprophylaxis. Thus there is no consensus dor the duration of the prophylaxis. There are authors that suggest extended prophylaxis up to 4 week after surgery. On the other hand, there are prospective randomized trials that inpatient (short-term up to 7-10 days) prophylaxis is adequate.

This is a retrospective cohort study with 89 patients who underwent major abdominal surgery for colorectal and gastric cancer. All patients received short term prophylaxis (during hospital stay only) rather than extended prophylaxis (4 weeks). All participants received duplex ultrasound in the study period for the diagnosis of deep vein thrombosis.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Deep Vein Thrombosis

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Older than 18 * Major abdominal surgery gor colorectal or gastric cancer * Caprini Risk score less than 9 * No history of anticoagulant treatment * Thromboprophylaxis during hospital stay only Exclusion Criteria: * Younger than 18 * Caprini Risk score 9 and above * History of anticogulants * Not reachable by phone etc

Outcomes

Primary Outcomes

The incidence of thromboembolic events by radiological assessment

All patients in the cohort received short time prophylaxis for deep vein thrombosis instead of prolonged duration. All patients will be assessed with ultrasound.

Time frame: 3 years follow up

Secondary Outcomes

Rate of predisposing factors of the patients

The patients with deep vein thrombosis in the cohort will be assessed according to their postoperative period features, histories, chemo treatments etc. with and questionnaire.