The colonoscopy procedure involves insertion of a thin, flexible tube with a tiny camera inside (colonoscope) passed inside the bowel. To allow passage of the colonoscope and adequate visualisation of the lining of the bowel wall a range of techniques can be used. During colonoscopy, you can distend the colon with water, CO2 and air. Air is no longer recommended for gas insufflation during colonoscopy as it causes pain and excess bowel distention. So the options are water and/or CO2 but it is not entirely clear which combination is the best and at what point during the colonoscopy. In practice, a hybrid technique where both CO2 and water are used during the colonoscopy in used. Here, water is exclusively used to help navigate the sigmoid colon with air pockets suctioned and turbid water exchanged with clean water. From splenic flexure to caecum a mixture of water and CO2 is used. The aim of this study is to assess procedure comfort and efficiency of two different colonoscopy insertion techniques: water-alone insertion of the colonoscope (gas insufflation not allowed on insertion; water exchange technique) versus water-CO2 hybrid insertion (water used predominately to splenic flexure with water/CO2 used to caecum; modified water immersion technique).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
SINGLE
Enrollment
246
Each arm is using a different colonoscopy insertion technique: either water-alone colonoscopy or water-CO2 colonoscopy.
St Mark's Hospital
Harrow, United Kingdom
Insertion time
Time taken to insert the colonoscope
Time frame: During procedure
Total procedure time
Time taken to insert and withdraw the colonoscope
Time frame: During procedure
Caecal intubation rate
The proportion of procedures where the caecum is reached
Time frame: During procedure
Patient discomfort scores
Patients will subjectively assess discomfort scores following the procedure using a Visual Analogue Scale (VAS) which ranges from 0 to 10 where a higher score means a worse outcome.
Time frame: Immediately after procedure
Loop formation
Scopeguide appearance will be used to evaluate number of loops formed
Time frame: During procedure
Adenoma detection rate
A measure of the number of adenomas detected during colonoscopy
Time frame: 1 week after procedure with results of histology
Serrated polyp detection rate
A measure of the number of serrated polyps detected during colonoscopy
Time frame: 1 week after procedure with results of histology
Number of ancilliary procedures
The number of patient repositions and abdominal pressure episodes required during the procedure
Time frame: During procedure
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