Data on switching from traditional mealtime insulins to fast-acting insulin aspart (Fiasp) in routine clinical practice are sparse. The aim was to evaluate the efficacy and safety of switching from traditional mealtime insulin to Fiasp in a "real-world" clinical practice setting in people with type 1 diabetes in Belgium.
The primary endpoint was the evolution of time in range (TIR, 70-180 mg/dl) at 6 and 12 months. Secondary endpoints included change in HbA1c, BMI, insulin doses, time below range (T\<70 and T\<54 mg/dl) and time above range (T\>180 and T\>250 mg/dl). Retrospective analysis Two-center study
Study Type
OBSERVATIONAL
Enrollment
438
Antwerp University Hospital
Edegem, Antwerp, Belgium
Time in Range
Time in target range at 12 months
Time frame: 12 months
Time in Range
Time in target range at 6 months
Time frame: 6 months
Change in HbA1c
Change in HbA1c
Time frame: 6 months & 12 months
Change in weight
Change in weight
Time frame: 6 months & 12 months
Change in insulin doses
Change in insulin doses
Time frame: 6 months & 12 months
Time below range
Change in time below range
Time frame: 6 months & 12 months
Time above range
Change in time above range
Time frame: 6 months & 12 months
Coefficient of variation
Change in coefficient of variation
Time frame: 6 months & 12 months
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