In France, the incidence of congenital hypothyroidism has increased significantly since the newborn screening program was introduced in 1978. The largest increase is seen in children with eutopic thyroid gland. More than one-third of children with eutopic gland have transient hypothyroidism. Clinical practice guidelines recommend to re-evaluate thyroid function in children with eutopic gland around the age of 3 years to determine whether hypothyroidism is transient or permanent. Up until today it is still difficult to determine early on whether hypothyroidism is transient or permanent in children with eutopic gland. Our aim is to identify one or more predictive factors for transient congenital hypothyroidism in children with eutopic gland or thyroid hemiagenesis.
Study Type
OBSERVATIONAL
Enrollment
60
CHRU Nancy
Nancy, France
Identify one or more predictive factors for transient congenital hypothyroidism in children with eutopic gland or thyroid hemiagenesis.
Time frame: 42 months
Compare the dose of Levothyroxine between children with transient and permanent congenital hypothyroidism at 6 months, 1 year, 2 years and 3 years follow-up.
Time frame: 6 months, 1 year, 2 years, 3 years
Assess the percentage of children with psychomotor impairment at the age of 3,5 years in both groups.
Time frame: 42 months
Assess how many children have had a hearing evaluation in both groups (excluding the newborn hearing screening).
Time frame: 42 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.