Evaluation of plasma angiotensin II and angiotensin II receptor levels in patients with sepsis and septic shock: a prospective observational study.
There is an increasing number of experimental publications investigated effects of angiotensin II and receptors on the pathogenesis and treatment of sepsis and septic shock. However, its level in humans and its relationship with the severity of the disease has not been investigated. If angiotensin II plays a role in the diagnosis and prognosis of septic shock by evaluating this relationship in our study, it may be a biomarker to be used in future diagnosis, prediction of prognosis and treatment. This will enable early recognition and treatment of this disease, which causes high mortality and cost in intensive care units, thus increasing the survival rate and reducing the cost.
Study Type
OBSERVATIONAL
Enrollment
75
Ayse Belin B OZER
Malatya, Turkey (Türkiye)
angiotensin II levels
serum angiotensin II levels
Time frame: 0-3 days
angiotensin II receptor I
serum angiotensin II receptor I levels
Time frame: 0-3 days
angiotensin II receptor II
serum angiotensin II receptor II levels
Time frame: 0-3 days
procalsitonine level
Procalsitonine level
Time frame: 0-3 days
crp level
crp levels
Time frame: 0-3 days
mortality
mortality rate
Time frame: 28 days
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