Adapt2Quit - An Adaptive Motivational System for Socio-Economically Disadvantaged Smokers

N/ACompletedNCT04720625

University of Massachusetts, Worcester757 enrolled

Overview

The goal of this research is to test the Adapt2Quit computer program that uses participant input (message rating on how much the text motivational message might influence one to quit smoking) to select and text motivational messages that are more likely to help a user stop smoking. This Adapt2Quit system will be compared with a quitline facilitation-only control (text messages will be sent to facilitate quitline use). The primary research hypothesis is that the Adapt2Quit recommender-selected messages will be more effective than a texting quitline facilitation-only control for smoking cessation among socioeconomically disadvantaged (SED) smokers.

The Adapt2Quit trial (NCT04720625) is a randomized controlled trial testing a machine-learning-driven text messaging system aimed at increasing smoking cessation rates among socioeconomically disadvantaged adults. The 6-month study compares an adaptive, personalized motivational messaging intervention against standard Quitline facilitation, utilizing AI to select tailored behavioral prompts based on user feedback.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

TRIPLE

Enrollment

757

Conditions

Tobacco Smoking

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 99 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Current smoker * Socioeconomically disadvantaged (SED) (using the following criteria: unemployed or underemployed, low income as defined by the federal poverty level guidelines, uninsured or underinsured, and/or have less than a high school education) * English-speaking * Active in care (at least two clinical visits in the last year) * Have a texting-enabled cell phone Exclusion Criteria: * Not a current smoker * Adults unable to consent * Individuals who are not yet adults (infants, children, teenagers) * Prisoners * Pregnant women * Pilot study participants

Locations (3)

Johns Hopkins University

Baltimore, Maryland, United States

Baystate Health

Springfield, Massachusetts, United States

University of Massachusetts Medical School

Worcester, Massachusetts, United States

Outcomes

Primary Outcomes

Number of Participants With Biochemically Verified 7-Day Point Prevalence Tobacco Abstinence at 6 Months

Participants who self-reported no tobacco use in the past 7 days at the 6-month follow-up underwent biochemical verification using the CoVita Smokerlyzer breath carbon monoxide (CO) monitor. Participants with a CO measurement of ≤6 ppm were classified as abstinent; those with a CO measurement of \>6 ppm were classified as tobacco users.

Time frame: 6-months post-randomization

Secondary Outcomes

Number of Participants With Self-Reported 7-Day Point Prevalence Cigarette Abstinence at 6 Months

Self-reported cigarette abstinence was assessed at the 6-month follow-up using the question: "Do you currently smoke cigarettes, even one puff in the last 7 days?" Participants who answered "No" were classified as self-reported abstinent.

Time frame: 6-months post-randomization