Evaluation of OE-MRI in Patients With H&N Cancer

Inclusion Criteria: Non-patient Volunteer Inclusion Criteria: * Age 18 years and above * Signed written informed consent Patient Inclusion Criteria: * Histologically proven or strong clinical suspicion of squamous cell carcinoma of the head and neck * Suitable for undergoing radical radiotherapy or chemoradiotherapy according to local protocols within the head and neck Cancer MDT * Age 18 years and above * Adequate physical fitness (WHO performance status 0 to 2) * Signed written informed consent Exclusion Criteria: Non-patient Volunteer Exclusion Criteria: * Contraindications to MRI scans as identified following completion of the Nottingham University Hospitals NHS Trust (NUH) standard MR safety screening protocol * Severe Chronic Obstructive Pulmonary Disease (COPD) who are at risk of type 2 respiratory failure or require supplemental oxygen * Volunteers who are pregnant as identified through the NUH standard MR safety screening protocol Patient Exclusion Criteria: * Poor physical fitness (WHO performance status greater than 2) * Contraindications to MRI scans as identified following completion of the NUH standard MR safety screening protocol * Severe Chronic Obstructive Pulmonary Disease (COPD) who are at risk of type 2 respiratory failure or require supplemental oxygen * Patients who are pregnant or breast-feeding (due to IV contrast use in the routine clinical scan) as identified through the NUH standard MR safety screening protocol