Define the effect of epidural block on HPV by EIT.
Epidural block may affect the physiological mechanism of hypoxic pulmonary vasoconstriction, which is still poorly understood. Electrical impedance tomography might be helpful in establishing the hypoxemia etiology at bedside via combining regional ventilation and perfusion information.
Study Type
OBSERVATIONAL
Enrollment
50
A bolus of 10ml 10% NaCl was injected during a respiratory pause (≥10s) through the central venous catheter.The results of arterial blood gas analysis and the data of EIT were collected before the first prone session (time baseline), the end of prone positioning (time P).
Zhongshan Hospital of Fudan University
Shanghai, Shanghai Municipality, China
RECRUITINGAssess regional distribution of pulmonary perfusion
To evaluate the effect of epidural block on pulmonary blood flow distribution.
Time frame: within 24 hours
Assess oxygenation status
To evaluate the effect of epidural block by assessing regional distribution of pulmonary perfusion based on indicator dilution and changes at different points in time during varying states of regional ventilation will be evaluated.
Time frame: within 24 hours
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