Impact of Early PCSK9 Inhibitor on Heart After Acute Myocardium Infarction

Inclusion Criteria: 1. Subject must be at least 18 years of age and less than 80 years old 2. Patients should have undergone successful percutaneous coronary intervention with drug-eluting stent for AMI and LAD should be the only culprit vessel. 3. Subject understand the study requirements and the treatment procedures and provided informed consent before the procedure Exclusion Criteria: 1. Female of childbearing potential, unless a recent pregnancy test is negative, who possibly plan to become pregnant any time after enrollment into this study 2. Known hypersensitivity or contraindication to study medications 3. Plan to receive revascularization in next six month. 4. Have received revascularization before. 5. Subjects with life expectation less than one year. 6. Subjects with active malignant tumor 7. subjects with severe liver or renal dysfunction（ALT \>5倍ULA，eGFR\<15ml/min/1.73mm2） 8. Other conditions which the investigators think not applicable to the study.