Arteriovenous Fistula Maturation Evaluation Study. FAME Study

Medifil AE86 enrolled

Overview

Study of the features of hemodynamic and clinical maturation of the native arteriovenous fistula for hemodialysis.

This is a prospective, single-center, observational study, investigating the clinical and hemodynamic features of maturation of hemodialysis native arteriovenous fistula (AVF). Hemodynamic features under investigation are the diameter of the feeding brachial artery, volume of flow (VF) measured with transcutaneous Duplex ultrasound (DUS), resistivity index (RI), diameter and wall thickness of the efferent vein, measured at days 1, 2, 3, 4, 5, 6, 7, 14, 21, 30, 60 and 90 post creation. Clinical features of maturation are the time of first access successful cannulation and the performance of three consecutive adequate dialysis sessions.

Study Type

OBSERVATIONAL

Enrollment

Conditions

End-stage Renal Disease Hemodialysis Access Failure Vascular Access Maturation Native Arteriovenous Fistula

Interventions

Doppler ultrasound studyDIAGNOSTIC_TEST

Transcutaneous Doppler ultrasound (DUS) study was performed at the mid brachial artery to assess diameter, VF and RI, and at the mid segment of the efferent vein to assess the diameter and wall thickness.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 95 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Hemodialysis patients 2. new native arteriovenous fistula (AVF) Exclusion Criteria: 1. Patients not eligible for AVF creation 2. Patients with non compensated heart failure New York Heart Association stages 3 and 4

Locations (1)

Mediterranean Hospital

Glyfada, Attica, Greece