Prognostic Biomarkers in Predicting Mortality in Respiratory Patients With Ventilator-Associated Pneumonia

Inclusion Criteria: * Respiratory failure needs mechanical ventilator support \> 48 hrs. VAP was defined as an acute lower respiratory tract infection in mechanically ventilated patient \> 48 hrs with a new or progressing infiltrate on chest radiograph and who met at least two of the following clinical criteria: body temperature \>38°C or \<36°C with no other recognized cause, white blood cell count \>10,000 /mm3 or \<5000 /mm3, or a macroscopically purulent tracheal aspirate * Only the first VAP episode was included Exclusion Criteria: * Neutropenia (\< 500 cells/ml) before the development of VAP. * Conditions are known to influence total and differential WBC counts such as chronic inflammatory conditions, hematologic disorders, history of chemotherapy, or radiotherapy within 4 weeks before enrollment. * Conditions are known to affect RDW as anemia due to nutritional deficiency (ie, iron, vitamin B12, and folic acid). * Patients with HIV/AIDS