Longitudinal study of 56 households with at least one member who had COVID-19 to compare the course of illness, immune responses, and long-term consequences of SARS-CoV-2 infection in HED patients with those of control subjects of the same age group. Complete households are investigated, including women who are pregnant when exposed to the virus and their newborn child(ren).
Study Type
OBSERVATIONAL
Enrollment
231
University Hospital Erlangen
Erlangen, Germany
age-dependence of SARS-CoV-2 infection
registry of household members with and without symptoms of COVID-19 (entire households)
Time frame: 3 months from the point in time at which the first household member shows symptoms of COVID-19
percentage of household members infected by SARS-CoV-2
The infection rate is determined on the basis of specific PCR tests and detectibility of antibodies against SARS-CoV-2.
Time frame: 3 months from the point in time at which the first household member shows symptoms of COVID-19
duration of primary COVID-19 symptoms
The possible association between the length of time with symptoms of COVID-19 and specific immune responses, in particular the development of virus-neutralizing antibodies, is studied.
Time frame: 2 months from the onset of COVID-19 symptoms
frequency of late-onset cardiovascular complications
Patient-reported known and yet unknown long-term consequences of COVID-19 are registered and investigated further (questionnaire, specific data confirmed by clinical examination).
Time frame: 2-12 months from the onset of COVID-19 symptoms
frequency of postviral fatigue
Patient-reported symptoms of fatigue are registered (questionnaire).
Time frame: 2-12 months from the onset of COVID-19 symptoms
frequency of noticeable temporary hair loss after COVID-19
Patient-reported extent of hair loss is registered (questionnaire).
Time frame: 2-12 months from the onset of COVID-19 symptoms
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.