Aim of the study is to examine the feasibility of dental implant insertion in patients receiving high, adjuvant and low dose \> 4 years.
The hypothesis of the present study is that dental implant therapy using submerged healing is feasible and predictable in patients receiving high, adjuvant or low dose AR for more than 4 years, as documented by clinical and radiographic signs of osseointegration after 3-4 months, sufficient implant stability for abutment connection, and implant survival rates comparable to those of healthy individuals after one year of prosthetic loading.
Study Type
OBSERVATIONAL
Enrollment
225
Dental surgery in patients treated with antiresorptive medication
Prosthetic treatment and loading of the dental implants
Copenhagen University Hospital, Maxillofacial Department
Copenhagen, Danmark, Denmark
RECRUITINGDental implant survival
Defined as presence of the implant in the jaw after initial implant surgery before abutment surgery
Time frame: 3 months
Dental implant survival
Defined as presence of the implant at time of final prosthetics
Time frame: 6 months
Dental implant survival
Defined as presence of the implant 1 year after loading of the final prosthetics
Time frame: 18 months
Dental implant survival
Defined as presence of the implant 2 years after loading of the final prosthetics
Time frame: 30 months
Dental Implant success
Defined as less marginal bone loss than 1.5 mm the first year, and 0.2 mm per year thereafter at time of assessment
Time frame: 30 months
Absence of medical related osteonecrosis of the jaw (MRONJ)
Defined as no exposed bone, no fistula, no radiologic sign of MRONJ
Time frame: 30 months
Oral Health Impact Profile
Using OHIP-14 questionnaire to evaluate oral health-related quality of life
Time frame: 30 months
EORTC QLQ-H&N 35
Performance of the EORTC questionnaire for the assessment of quality of life in head and neck cancer patients
Time frame: 30 months
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