HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial

Ability to independently walk 3 meters

Ability to independently walk 3 meters (10 feet) or across a room without human assistance. Patients who require a cane or walker, but not human assistance, will be classified as able to walk independently. Patients who require assistance to get out of a chair, but can walk independently once they get up, will be classified as able to walk independently.

Time frame: Within 90 days post randomization

Composite of major complications

Composite includes vascular and nonvascular mortality, non-fatal myocardial infarction, acute congestive heart failure, and stroke.

Time frame: Within 90 days post randomization

Vascular mortality

Any death with a vascular cause and includes those deaths following a myocardial infarction, sudden cardiac arrest, stroke, cardiac revascularization procedure (i.e., percutaneous coronary intervention \[PCI\] or coronary artery bypass graft \[CABG\] surgery), heart failure, pulmonary embolus, cardiovascular hemorrhage, or deaths due to an unknown cause

Time frame: Within 90 days post randomization

Nonvascular mortality

Any death due to a clearly documented non-vascular cause.

Time frame: Within 90 days post randomization

Myocardial Infarction

Diagnosis of MI according to 4th universal definition of myocardial infarction

Time frame: Within 90 days post randomization

Acute Congestive Heart Failure

at least one clinical sign(s) or symptom(s) (e.g elevated jugular venous pressure, respiratory rales/crackles, crepitations, hypoxia, tachypnea or presence of S3) with at least one of the following: 1. radiographic findings (i.e., vascular redistribution, interstitial pulmonary edema, or frank alveolar pulmonary edema) or point of care ultrasound findings (i.e., bilateral B-lines, bilateral pleural effusion, elevated jugular venous pressure, dilated inferior vena cava with respiratory variation less than 50%) OR 2. heart failure treatment implemented with diuretics with documented clinical improvement.

Time frame: Within 90 days post randomization

Stroke

Either - 1. a new focal neurological deficit thought to be vascular in origin with signs or symptoms lasting more than 24 hours or leading to death; or 2. a new focal neurological deficit thought to be vascular in origin with signs or symptoms lasting less 24 hours with a positive neuroimaging consistent with a stroke

Time frame: Within 90 days post randomization

Time from randomization to hospital discharge

Length of hospital stay from randomization to hospital discharge

Time frame: Within 90 days post randomization

Delirium

1. Patient meets the criteria for delirium on any in-person 3D-CAM or CAM administered; OR 2. Positive history of delirium in the 7 days after randomization based on the review of hospital health records.

Time frame: Within 7 days and 90 days post randomization

Moderate to severe pain

Moderate to severe pain is defined as any pain score ≥3 on 10 points scale.

Time frame: Within 7 days and 90 days post randomization