Intrathecal Additives for Spinal Anaesthesia in Elective Caesarean Sections

Benha University105 enrolled

Overview

we designed this randomized, single -blind, prospective clinical study to test postoperative analgesia of three intrathecal additives in elective caesarean sections which are magnesium, dexamethasone and dexmedetomidine.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Enrollment

105

Conditions

Pain, Postoperative

Interventions

intrathecal MagnesiumDRUG

intrathecal adjuvants to bupivacaine

intrathecal dexamthasoneDRUG

intrathecal adjuvants to bupivacaine

intrathecal dexmedetomidineDRUG

intrathecal adjuvants to bupivacaine

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * American Society of Anesthesiologists classII-III adult female patient (age :18 -40 years old ) * Elective cesarean section under spinal anaesthesia * Gestational age \> 37 weeks * BMI less than 30 kg/m2 Exclusion Criteria: * Patient refusal * unable to give consent * age \< 18 or \> 40 * BMI more than 30 kg/m2 * known allergy to the study medication * coagulopathies or on anticoagulant medications * diabetic neuropathy * patients with psychiatric disorders

Outcomes

Primary Outcomes

analgesic effect

duration of sensory block

Time frame: Up to 24 hours after surgery

Data from ClinicalTrials.gov

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