The aim is to investigate if iron deficiency at the time of colorectal cancer diagnosis has an influence on fatigue, quality of life, cognition and physical ability.
Around 60% of newly diagnosed colorectal cancer patients suffer from iron deficiency at the time of diagnosis. The study hypothesis is that, besides leading to anemia, iron deficiency might be associated with impaired patient report outcomes in the domains of fatigue, quality of life, cognitive impairment and lower physical ability. No previous studies on colorectal cancer patients and iron deficiency are available. The participants (patients suspected of colorectal cancer after endoscopy) will be tested on these parameters. The participants and the investigators are blinded to the patients iron status. The study takes place before any preoperative iron treatment. Multivariate analysis will be used taking into account, gender, age, hemoglobin, tumor stage.
Study Type
OBSERVATIONAL
Enrollment
200
Its not an intervention. Its an observational study. The groups are defined based on their iron status
Sygehus Sønderjylland
Aabenraa, Region Syddanmark, Denmark
Hospital of South West Jutland
Esbjerg, Region Syddanmark, Denmark
Hospital of South West Jutland
Grindsted, Region Syddanmark, Denmark
Fatigue
Fatigue sub-scale of Focussed assessment of cancer treatment - anemia
Time frame: up to one months after inclusion
Quality of life
European Organisation for Research and Treatment of Cancer C30
Time frame: up to one months after inclusion
Cognitive ability
Montreal cognitive assessment
Time frame: up to one months after inclusion
endurance
6 minutes walk test
Time frame: up to one months after inclusion
peripheral muscular strengths
hand-held dynamometer
Time frame: up to one months after inclusion
mobility and balance
timed-up-and-go-test
Time frame: up to one months after inclusion
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