Comparison of Efficacy and Tolerability of APD Treatment With Different PD Cyclers

Inclusion Criteria: * Informed consent signed and dated by study patient and investigator/authorised physician * CKD patients being treated with APD for at least 3 months * Minimum age of 18 years * Body weight ≥ 40 kg * Fluid status regularly monitored with Body Composition Monitor (BCM) * Patients planned to change to the Silencia PD cycler * Proper functioning catheter * Intraperitoneal Pressure (IPP) ≤ 18 cm H2O for the maximum of TAVO parameter "permitted patient volume" * Ability to understand the nature and requirements of the study Exclusion Criteria: * Patients who have any condition prohibiting the use of BCM, like patients with major amputations (e.g. lower leg) * Patients receiving polyglucose containing PD solution * Any conditions which could interfere with the patient's ability to comply with the study * Patients who suffer from peritonitis/exit site infection during the last 4 weeks * Women of childbearing age without effective means of contraception, pregnancy (pregnancy test will be conducted at start and end of study) or lactation period * Life expectancy \< 3 months * Participation in an interventional clinical study during the preceding 30 days * Previous participation in the same study