Epilepsy is a neurological disease that can cause many comorbid psychiatric disorders, among them: generalized anxiety disorder and depression. Many studies suggest a temporal relationship between exposure to a traumatic event and the development of epilepsy. The objective of this research is to study the symptoms of post-traumatic stress disorder (PTS) in patients with epilepsy, and their relation to anxiety and depression in these patients. The investigators also wish to study how such symptoms may be associated with the subjective semiological manifestations of epileptic seizures. In addition, it has been shown that patients with epilepsy are able, from the identification of different warning signs, to anticipate their vulnerability to having an epileptic seizure allowing them to set up different types. strategies to control them. The investigators also wish to study the cognitive processes involved in this control and the influence of PTS symptoms, in particular hypervigilance on this behavior. The investigators propose a protocol using different types of measures: emotional, cognitive and physiological in order to answer our questions. In addition to patients with epilepsy, two groups of patients will be included: a group of patients with another chronic non-neurological disease to compare the prevalence of PTS symptoms and a group of patients with post-traumatic stress disorder ( PTSD) to compare with patients with epilepsy, cognitive and physiological measures. Finally, the results of this study should allow to develop tools for assessing PTS symptoms in epilepsy and to develop specific management approaches
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
129
Surveys, interviews and measures
Assistance Publique Hopitaux de Marseille
Marseille, France
Anxiety level
Beck Anxiety inventory (0-63), higher values mean worse outcome
Time frame: Baseline
Depression
Beck Anxiety inventory (0-21), higher values mean worse outcome
Time frame: Baseline
Number of patients with PTSD
Post-traumatic stress disorder
Time frame: Baseline
Emotion regulation
The difficulties in emotion regulation scale,(0-180), higher values mean better outcome
Time frame: Baseline
Quality of life of the patient
Medical Outcome Study and 36-item Short Form Health Survey (0-60),higher values mean worse outcome
Time frame: Baseline
Seizures control
Seizure control scale (0-85), higher values mean better outcome
Time frame: Baseline
Seizures control (heart rythm)
HRSC
Time frame: Baseline
PTSD
PTSD-E (0-100), higher values mean worse outcome
Time frame: Baseline
Emotionnal control of diabete
DID-C (Diabete insulino-dependant-Control) (elaborated for the study) (0-150), higher values mean worse outcome
Time frame: Baseline
Emotionnal control of diabete and PTSD
DID-PTSD (Diabete insulino-dependant-Posttraumatic Stress Disorder) (elaborated for the study) (0-185), higher values mean worse outcome
Time frame: Baseline
Skin conductance
BIOPAC SCL (EDA 100C)
Time frame: Baseline
Eyes movements
EyeLink 1000 (SR Research)
Time frame: Baseline
Heart rythm variability
BIOPAC ECG (EL250)
Time frame: Baseline
Attentional and executive control
Attentional and executive control task in the context of hypervigilance (elaborated for the study) (0-180), higher values mean worse outcome
Time frame: Baseline
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