The study aims to investigate SARS-CoV-2 susceptibility, transmission and disease severity in healthcare workers and patients. Residual specimens from an existing collection of samples in viral inactivating buffer and derivatives and serum from the Crick COVID-19 Consortium Testing centre (Cohort A1) and additional biological material collected prospectively (Cohorts A2 and B) will be used for research into SARS-CoV-2 transmission, evolution and immune control. This testing centre is a partnership between UCLH and The Francis Crick Institute to provide COVID 19 RT PCR testing for healthcare workers (HCWs) and patients in London Hospitals and care homes. A third group (Cohort C) of the study will allow for collaborative work with other REC approved research studies that have used the Crick COVID-19 Consortium Testing centre and will involve the use of study samples already collected from each study to be analysed under the SARS-CoV-2 Longitudinal Study end points
Study Type
OBSERVATIONAL
Enrollment
6,000
Ealing and Northwick Park hospital
London, United Kingdom
RECRUITINGThe Francis Crick Institute
London, United Kingdom
RECRUITINGUCLH
London, United Kingdom
RECRUITINGSARS-CoV-2 susceptibility in healthcare workers and patients
To investigate SARS-CoV-2 susceptibility by examining the number of positive SARS-CoV-2 result per participant
Time frame: 24 months
SARS-CoV-2 transmission in healthcare workers and patients
To investigate SARS-CoV-2 transmission by analysis of samples sequencing data from each study centre and across study centres
Time frame: 24 months
SARS-CoV-2 severity in healthcare workers and patients
To investigate SARS-CoV-2 severity by review of symptom severity
Time frame: 24 months
SARS-CoV-2 severity in healthcare workers and patients
To investigate SARS-CoV-2 severity by review of any hospital admissions
Time frame: 24 months
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