Small bowel obstruction (SBO) is a common and potentially life-threatening acute surgical condition. A minority of patients present with a clear indication for urgent surgical intervention, either on the basis of clinical or radiological assessment (clinical signs of peritonitis/sepsis; suspicion of bowel ischaemia; closed loop obstructions; irreducible herniae etc.). However, the optimal management of the remaining patients, the majority of whom present with SBO caused by abdominal adhesions, remains a topic of international debate with practice varying in different healthcare systems. This multicentre, prospective, observational study aims to describe the current management of patients admitted with SBO in 6 acute hospitals (Bispebjerg, Herlev, Hillerød, Hvidovre, Køge, Slagelse) on the island of Sjælland, Denmark, which accounts for a 1/3 of the total Danish population.
This is a prospective, non-interventional observational study of the management and outcomes of patients admitted with SBO in Denmark. Relevant clinicopathological demographics will be retrieved from consenting patients' medical records. An initial analysis will be performed once these patients have reached 90 days follow-up after the start of treatment. The long-term outcomes of treatment will be assessed with further analyses at 1, 3 and 5 years follow-up.
Study Type
OBSERVATIONAL
Enrollment
540
Bispebjerg Hospital
Copenhagen, County, Denmark
Herlev Hospital
Copenhagen, Denmark
Hvidovre Hospital
Copenhagen, Denmark
Hillerød Hospital
Hillerød, Denmark
Zealand University Hospital
Køge, Denmark
Slagelse Hospital
Slagelse, Denmark
30-day morbidity rate
Time frame: 30 days
30-day mortality rate
Time frame: 30 days
90-day mortality rate
Time frame: 90 days
To describe the proportion of patients undergoing operative versus non-operative management
Time frame: From 90 days
To determine the success rate of non-operative management in patients with SBO and identify predictors of success/failure
Time frame: From the start of treatment until 90-days follow-up
To determine the incidence and consequence of acute kidney injury in patients with SBO
Time frame: 90 days
To determine the incidence and consequence of malnourishment in patients with SBO
Time frame: 90 days
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