Amitriptyline vs GON and SON Blocks in Migraine

Dr. Lutfi Kirdar Kartal Training and Research Hospital57 enrolled

Overview

Comparison of efficacy and safety of amitriptyline and nerve blocks

This study aims to compare the efficacy and safety of amitriptyline and nerve blocks (greater occipital nerve and supraorbital nerve)

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Migraine Headache

Interventions

Lidocaine 1% Injectable SolutionDRUG

Repeated injections of lidocaine to greater occipital nerve and supraorbital nerve once a week for first four weeks then once a month for five months

AmitriptylineDRUG

Amitriptyline 25 mg daily

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosed with migraine according to ICHD-3 Exclusion Criteria: * Being over 50 years or under 18 years * Malignancy and other systemic diseases

Locations (1)

Cem Bölük

Istanbul, Fatih, Turkey (Türkiye)

Outcomes

Primary Outcomes

Number of Participants with 50% Reduction of Headache Frequency

Monthly headache frequency will be followed

Time frame: 6 months

Secondary Outcomes

Side effects

Major and minor side effects will be followed

Time frame: 6 months

Data from ClinicalTrials.gov

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