nCap Pain Relief Patch vs. Placebo

Inclusion Criteria: * Meet Altman's clinical criteria for Knee Osteoarthritis * Male and Female Adults age 40-79 * VAS pain score of \> 4 at the beginning of the study Exclusion Criteria: * Subject unable to walk unassisted. Participants must be able to stand/walk for 30 minutes * Inability to read and understand English. Must be able to complete WOMAC scale and questionnaires * Severe systemic disease limiting ability to ambulate for 30 minutes * Use of a TENS unit for one week before study or during study * History of total knee replacement on the affected knee * Knee surgery on the affected knee in the last 12 months * Injection into the knee in the last 6 months * Knee pain \< 411 * Inability to cognitively understand consent form or research study, or inability to give consent * Diagnosis of fibromyalgia, rheumatoid arthritis, gout, dysplasia, septic arthritis, knee pain from other diseases. * Malignancy * Injury to knee within 6 months * Concomitant use of opioids, NSAIDS or other analgesics for 1 week before trial (or 5 half-lives, whichever is greater)9, or during trial with exception of acetaminophen. * Pregnant or lactating * Poor general health (ASA classification of IV+)