To assess the impact of a muscle-targeted nutritional therapy consisting of nutritional counseling and high-quality whey protein-based oral nutritional supplements enriched with leucine and vitamin D, on the recovery of post-COVID-19 patients
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
5
Patients will receive daily for 12 weeks two servings (40 grams each) of powder (Fortifit; Nutricia) which has to be dissolved in 125 ml of water. Per serving, 20 g whey protein, 3 g total leucine, 9 g carbohydrates, 3 g fat, and 800 IU vitamin D. Patients will be also followed for 12 weeks after the suspension of supplementation.
Fondazione IRCCS Policlinico San Matteo
Pavia, Italy
Physical performance - chair-stand
Change in chair-stand test
Time frame: 12 weeks
Physical performance - chair-stand
Change in chair-stand test at the end of study
Time frame: 24 weeks
Total body muscle mass
Change in total body muscle mass during the study
Time frame: 24 weeks
Appendicular muscle mass
Change in appendicular muscle mass during the study
Time frame: 24 weeks
Functional status - muscle strength
Change in handgrip strength during the study
Time frame: 24 weeks
Fatigue
Change in fatigue as assessed by the Functional Assessment of Chronic Illness Therapy Fatigue (FACIT-F) during the study
Time frame: 24 weeks
Energy intake
Change in energy intake during the study
Time frame: 24 weeks
Self-perceived quality of life
Change in quality of life during the study as assessed by the five-level EuroQol five-dimensional (EQ-5D-5L) descriptive system during the study
Time frame: 24 weeks
Body weight
Change in body weight during the study
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Time frame: 24 weeks
Serum levels of 25-hydroxy-vitamin D
Change in 25-hydroxy-vitamin D during the study
Time frame: 24 weeks