The study is designed to determine whether hemorrhage within the injured spinal cord is influenced by mean arterial pressure (MAP) augmentation with vasopressors and by venous thromboembolism (VTE) prophylaxis with anticoagulants in the first two weeks following a traumatic spinal cord injury (tSCI).
This will be a single-center prospective observational study of patients with an acute cervical traumatic spinal cord injury
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
24
Serial MRI scans of patients with acute cervical SCI to quantify hemorrhage.
Vancouver General Hospital
Vancouver, British Columbia, Canada
RECRUITINGHemorrhage Quantification 1
Area of hematoma
Time frame: Serial MRI assessments: Injury to 2 weeks post injury
Hemorrhage Quantification 2
Vertical length of hematoma and vertical length of cord edema
Time frame: Serial MRI assessments: Injury to 2 weeks post injury
Hemorrhage Quantification 3
The point of maximum cord compression vertebral level and anatomic point of maximum cord compression vertebral sublevel
Time frame: Serial MRI assessments: Injury to 2 weeks post injury
Hemorrhage Quantification 4
Vertical length of cord edema rostral to maximum compression and vertical length of cord edema caudal to maximum compression.
Time frame: Serial MRI assessments: Injury to 2 weeks post injury
Hemodynamic Management Assessment 1
achieved mean arterial pressure
Time frame: Injury to 2 weeks post injury
Hemodynamic Management Assessment 2
vasopressor usage/dose
Time frame: Injury to 2 weeks post injury
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