Adolescent Idiopathic Scoliosis (AIS) is the most frequent spinal deformity in adolescence, but its etiology remains unknown. Recent publications suggest a link between ciliopathy and AIS. More specifically a modification of the cerebro-spinal fluid (CSF) flow by ciliary dysfunction could be at the origin of a scoliotic deformity. This study aims to compare the CSF flow measured by magnetic resonance imaging (MRI) in an AIS group and a control group.
Study Type
OBSERVATIONAL
Enrollment
72
Evaluations of Postural control; Subjective postural vertical; Subjective visual vertical; Verticality perception
Non-injected CSF flow MRI
Evaluations of Postural control; Subjective postural vertical; Subjective visual vertical; Verticality perception
SSR Pédiatrique Marc Sautelet
Villeneuve-d'Ascq, Nord (59), France
GHICL Hôpital Saint Philibert, service d'Imagerie Médicale
Lomme, Nord, France
CSF flow (cm/s) at the 7th thoracic vertebra (T7)
The flow will be measured by MRI
Time frame: 6 months
CSF flow (cm/s) at the cervico-occipital junction
The flow will be measured by MRI
Time frame: 6 months
CSF flow (cm/s) at the cerebral aqueduct
The flow will be measured by MRI
Time frame: 6 months
Prevalence of spinal cord abnormalities
Measured by MRI
Time frame: 6 months
Correlation between the Body Mass Index and the CSF flow (cm/s) at the 7th thoracic vertebra (T7)
This association will be studied by a linear regression analysis
Time frame: 6 months
Cobb frontal angle in degrees
The measurement of radiographic parameters will be done with the EOS system. The EOS system is a new slot-scanning radiological device that allows simultaneous acquisition of frontal and lateral images. It is composed of two X-ray sources, shaped as fan beams through collimation slits.
Time frame: 6 month
Distance between the vertical line passing through the middle of the sacrum and the vertical line passing through the spine of the 7th cervical vertebra.
Time frame: 6 month
Angle of thoracic kyphosis T4-T12 in degrees
The measurement of radiographic parameters will be done with the EOS system.
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Non-injected CSF flow MRI
Time frame: 6 months
Lumbar lordosis angle L1-L5 in degrees
The measurement of radiographic parameters will be done with the EOS system.
Time frame: 6 months
Lumbo-sacral angle L5-S1 in degrees
The measurement of radiographic parameters will be done with the EOS system The measurement of radiographic parameters will be done with the EOS system.
Time frame: 6 months
Pelvic incidence in degrees
The measurement of radiographic parameters will be done with the EOS system
Time frame: 6 months
Subjective Postural Vertical Measurement in degrees
Time frame: 6 months
Subjective Visual Vertical Sight Measurement in degrees
Time frame: 6 months
Proprioception Measurement in degrees
Proprioception measurement obtained by trunk repositioning error test (Formetric system)
Time frame: 6 months