The aim of the current study is to evaluate the safety and efficay of cilostazol in treatment of patients with fatty liver disease. Several previous reports have shown that cilostazol ameliorates lipid imbalances in NAFLD. Cilostazol appeared to exert beneficial effects against NAFLD
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Cilostazol 50 MG tablet twice daily
Placebo tablet twice daily
Faculty of Pharmacy
Shibīn al Kawm, Menoufia, Egypt
Hepatic transaminases
Alanine aminotransferase (ALT) and Aspartate Aminotransferase (AST) will be evaluated in U/L
Time frame: week 12
Serum ferritin
Serum ferritin
Time frame: week 12
Lipid profile
Total cholesterol (mg/dL), LDL-cholesterol (mg/dL), HDL-cholesterol (mg/dL), VLDL-cholesterol (mg/dL) and triglycerides (mg/dL) will be measured before and after the intervention.
Time frame: week 12
Glycated haemoglobin
Hb A1c (%)
Time frame: week 12
Serum stem cell transforming factor beta
Serum stem cell transforming factor beta
Time frame: 12 weeks
Adverse effects
Adverse effects
Time frame: 12 weeks
FAM19A5 serum level
FAM19A5 serum level
Time frame: 12 weeks
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