Aging, renal pathology (eg SLE, ADPKD), X-ray exposition and pharmacological treatments, especially previous strong immunosuppression, may negatively influence the ovarian reserve in childbearing age women. Anti-Müllerian hormone (AMH) is regarded as biomarker for ovarian reserve. Every female with renal disease regularly menstruating that met exclusion criteria could have participated. The aim was to assess ovarian reserve in female patients with normal menstrual cycle and kidney disease, including kidney transplant recipients.
Study Type
OBSERVATIONAL
Enrollment
153
AMH level measurement using ELISA test from blood samples
Nephrology and Transplantation Clinic University Hospital in Wrocław
Wroclaw, Poland
To compare AMH levels between three groups
Serum AMH levels \[ng/ml\] measured using ELISA and compared between three groups
Time frame: 1 day
Potential impact of X-ray exposition on ovarian reserve
Analysis of the impact of X-ray exposition \[mSv\] on AMH serum level \[ng/ml\]
Time frame: 1 day
Potential impact of antiproliferative drugs on ovarian reserve
Analysis of the impact of antiproliferative drugs on AMH serum level \[ng/ml\]
Time frame: 1 day
Potential impact of underlying kidney disease on ovarian reserve
Analysis of the impact of underlying kidney disease (including SLE) on AMH serum level \[ng/ml\]
Time frame: 1 day
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