Post Approval Study2: Hintermann Series H3 Total Ankle Replacement System

Inclusion Criteria: * Each potential subject must be an appropriate candidate for mobile bearing TAR by having: a primary osteoarthritis, post-traumatic osteoarthritis, or arthritis secondary to inflammatory disease, as determined by the Principle Investigator. * Willingness to participate in the study and follow-up visits * Written informed consent, including authorization to release collected health data Exclusion Criteria: * Skeletal immaturity * Bone stock inadequate to support the device including: * Severe osteoporotic or osteopenic condition or other conditions resulting in poor bone quality * Avascular necrosis of the talus * Active or prior deep infection in the ankle joint or adjacent bones * Malalignment or severe deformity of involved or adjacent anatomic structures including: * Hindfoot or forefoot malalignment precluding plantigrade foot * Significant malalignment of the knee joint * Insufficient ligament support that cannot be repaired with soft tissue stabilization (syndesmosis disruption) * Charcot joint or peripheral neuropathy that may lead to Charcot joint of the affected ankle * Neuromuscular disease resulting in lack of normal muscle function about the affected ankle * Lower extremity vascular insufficiency demonstrated by Doppler arterial pressure * Poor skin and soft tissue quality about the surgical site * Immunosupressive therapy * Prior ankle fusion or revision of total ankle replacement * High demanding sport activities (e.g., contact sports, jumping) * Suspected or documented metal allergy or intolerance * Condition or situation which, in the Physician's opinion, puts the subject at significant risk, or may interfere significantly with the subject's participation in the study